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1. Mild to moderate

trimethoprim/ sulfamethoxazole
160 mg/800 mg tablet, bidx 10 days
$2.44/10 days

or amoxicillin/clavulanate
500 mg/125 mg tablet, tidx 10 days
$40.80/10 days

or cefuroxime axetil
500 mg, bid x 10 days
$57.35/10 days

AND, If Legionella is suspected, to any of the above add 1 of the following:

erythromycin base
1 g/day, divided bid to qidx 3 weeks
$3.81/3 weeks

or azithromycin
500 mg, once on first day, then 250 mg, once daily x 4 days
$29.60/5 days

or clarithromycin
250 mg, bid x 3 weeks
$62.12/3 weeks

2. Severe

i. penicillin V
600 mg, qid x 10 days
$3.17/10 days

AND

ciprofloxacin
500-750, mg bid x 10 days
$50.12-94.52/10 days

OR

ii. cefuroxime axetil
500 mg, bid x 10 days
$57.35/10 days

OR

iii. ceftriaxone
0.5-1 g IM, bid x 10 days
$340.00-670.00/10 days

AND, if Legionella is suspected, to any of the above add 1 of the following:

erythromycin base
1 g/day, divided bid to qid x3 weeks
$3.81/3 weeks

or azithromycin
500 mg, once on first day, then 250 mg, once daily x 4 days
$29.60/5 days

or clarithromycin
250 mg, bid x 3 weeks
$62.12/3 weeks

Second-line therapies:

For severe cases and patient allergic to penicillin

ciprofloxacin
500-750 mg, bid x 10 days
$50.12-94.52/10 days

AND

clindamycin
1.2-2.4 g/day IM, divided bid to qid x 10 days
$261.36-522.72/10 days

Additional instructions and notes

-There is no difference in efficacy between the 3 first-line agents (trimethoprim/sulfamethoxazole, cefuroxime axetil and amoxicillin/clavulanate) but there is a major difference in price.

-Other erythromycins, including modified-release preparations, may be 2-7 times more expensive than erythromycin base.

1 out of 1 people agree

David C.

Created Friday 05 October 2007 - 19:13 PM

Updated Thursday 15 November 2007 - 10:18 AM

This is slightly dated but otherwise not bad

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