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APO-DESMOPRESSIN 0.1MG

Posted Wednesday 05 December 2007 - 18:09 PM by John Sollazzo ( HIGH significance )

ATC Code

H01BA02

Warning

Risk of hyponatremia with this drug.
The FDA recommends that:
* children with primary nocturnal enuresis not be given the intranasal formulation, and that physicians "should consider other options";
* patients taking desmopressin tablets stop treatment during periods of fluid and electrolyte imbalance (e.g., fever, recurrent diarrhea or vomiting, intense exercise, or other conditions associated with increased water intake);
* all formulations be used cautiously in patients "with habitual or psychogenic polydipsia or in patients who are taking drugs that may cause them to drink more fluids, such as tricyclic antidepressants and [SSRIs]."

Evidence

Good

Reference

http://www.fda.gov/cder/drug/InfoSheets/HCP/des...

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