Users

NOVO VENLAFAXINE XR

Posted Thursday 30 October 2008 - 09:33 AM by David Chan ( HIGH significance )

ATC Code

N06AX16

Warning

Venlafaxine HCl Extended-Release Capsule manufacturers wish to provide you with important safety information regarding venlafaxine XR. Published retrospective studies 1,2,3,4 have reported that venlafaxine overdosage may be associated with an increased risk of fatal outcome compared to that observed with Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants, but lower than that for tricyclic antidepressants. Although the extent to which the finding of an increased risk of fatal outcomes can be attributed to the toxicity of venlafaxine in overdosage, as opposed to some characteristics of venlafaxine-treated patients, is not clear,5 post-market reports of fatal acute overdoses have been received for venlafaxine alone at doses as low as approximately 1 gram.

Evidence

Good

Reference

http://www.hc-sc.gc.ca/dhp-mps/medeff/advisorie...

No comments so far

Search Posts







Search Tips


Get RSS Feeds!

MyDrugRef now offers RSS Feeds. Click here to get them!